B3gat3^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: B3gat3^m2Btlr
• Name: beta-1,3-glucuronyltransferase 3; mutation 2, Bruce Beutler
• MGI ID: MGI:6761402
• Synonyms: B3gat3^Y191C
• Gene: B3gat3 Location: Chr19:8897740-8904600 bp, + strand Genetic Position: Chr19, 6.03 cM, cytoband A
• Alliance: B3gat3^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A-to-G point mutation that results in the amino acid substitution of tyrosine with cysteine at position 191 (p.Y191C). (J:309727)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any B3gat3 Mutation: 8 strains or lines available

References

• Original: J:309727 Rios JJ, et al., Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice. J Bone Miner Res. 2021 Aug;36(8):1548-1565
• All: 1 reference(s)