Kpna6^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Kpna6^m1Btlr
• Name: karyopherin subunit alpha 6; mutation 1, Bruce Beutler
• MGI ID: MGI:6761425
• Synonyms: Kpna6^Q436X
• Gene: Kpna6 Location: Chr4:129537773-129566560 bp, - strand Genetic Position: Chr4, 63.28 cM, cytoband D2.3
• Alliance: Kpna6^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis produced a G-to-A point mutation that results in the amino acid substitution of glutamine with a stop codon at position 436 (p.Q436*). (J:309727)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kpna6 Mutation: 44 strains or lines available

References

• Original: J:309727 Rios JJ, et al., Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice. J Bone Miner Res. 2021 Aug;36(8):1548-1565
• All: 1 reference(s)