Arid4a^em1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Arid4a^em1Btlr
• Name: AT-rich interaction domain 4A; endonuclease-mediated mutation 1, Bruce Beutler
• MGI ID: MGI:6761445
• Synonyms: Arid4a^{p.Asn263AspfsTer1}
• Gene: Arid4a Location: Chr12:71062764-71145366 bp, + strand Genetic Position: Chr12, 29.39 cM
• Alliance: Arid4a^em1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR-targeting produced a deletion-insertion mutation (chr12:71094015_71094058delAATTGGAAAATGGATATAAGTGAAATCCTTGAGTCCTCCAGCAGinsGAT (GRCm39)) resulting in a frameshift and premature stop codon (p.Asn263Aspfs*2). (J:309727)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arid4a Mutation: 60 strains or lines available

References

• Original: J:309727 Rios JJ, et al., Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice. J Bone Miner Res. 2021 Aug;36(8):1548-1565
• All: 1 reference(s)