Rps21^em1Utr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rps21^em1Utr
• Name: ribosomal protein S21; endonuclease-mediated mutation 1, University of Tsukuba Laboratory Animal Resource Center
• MGI ID: MGI:6761756
• Synonyms: Rps21^d
• Gene: Rps21 Location: Chr2:179899172-179900237 bp, + strand Genetic Position: Chr2, 102.78 cM
• Alliance: Rps21^em1Utr page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 2-6 was deleted using sgRNAs targeting intron 1 and the intergenic region downstream of exon 6 with CRISPR/Cas9 technology. (J:309963)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rps21 Mutation: 12 strains or lines available

References

• Original: J:309963 Dinh TTH, et al., Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway. Elife. 2021 May 5;10:e50346
• All: 1 reference(s)