Habp4^em1Jkob
Endonuclease-mediated Allele Detail

Summary

• Symbol: Habp4^em1Jkob
• Name: hyaluronic acid binding protein 4; endonuclease-mediated mutation 1, Jorg Kobarg
• MGI ID: MGI:6763956
• Gene: Habp4 Location: Chr13:64309680-64334351 bp, + strand Genetic Position: Chr13, 33.26 cM, cytoband B3
• Alliance: Habp4^em1Jkob page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Intragenic deletion, Nucleotide substitutions
• Mutation details: CRISPR/Cas9 technology generated a 17 bp deletion (GCGTCGCGATGAGGCGG) and 3 bp substitution (GGCGGCG to TGCTGCA) in exon 1. (J:310581)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Habp4 Mutation: 13 strains or lines available

References

• Original: J:310581 Melo-Hanchuk TD, et al., Intracellular hyaluronic acid-binding protein 4 (HABP4): a candidate tumor suppressor in colorectal cancer. Oncotarget. 2020 Nov 17;11(46):4325-4337
• All: 1 reference(s)