Spink7^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spink7^em1Cya
• Name: serine peptidase inhibitor, Kazal type 7 (putative); endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6764496
• Synonyms: Spink7^em1Cgen, Spink7^em1cyagen
• Gene: Spink7 Location: Chr18:62725265-62729398 bp, - strand Genetic Position: Chr18, 35.33 cM
• Alliance: Spink7^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exons 2 and 3 deleted 1036 bp. (J:310883)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spink7 Mutation: 12 strains or lines available

References

• Original: J:310883 Zhao N, et al., Neutrophils-derived Spink7 as one safeguard against experimental murine colitis. Biochim Biophys Acta Mol Basis Dis. 2021 Jun 1;1867(6):166125
• All: 1 reference(s)