Tuba3b^em1Smtb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tuba3b^em1Smtb
• Name: tubulin, alpha 3B; endonuclease-mediated mutation 1, Shogo Matoba
• MGI ID: MGI:6764561
• Gene: Tuba3b Location: Chr6:145561689-145567203 bp, + strand Genetic Position: Chr6, 77.62 cM
• Alliance: Tuba3b^em1Smtb page

Mutation origin

• Strain of Origin: C57BL/6NSlc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting of exons 3 and 4 produced an in/del knockout mutation. (J:308859)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tuba3b Mutation: 21 strains or lines available

References

• Original: J:308859 Akter MS, et al., CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice. Sci Rep. 2021 Jul 29;11(1):15438
• All: 1 reference(s)