Trpc4ap^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trpc4ap^em1Cya
• Name: transient receptor potential cation channel, subfamily C, member 4 associated protein; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6765363
• Synonyms: Trpc4ap^em1Cgen, Trpc4ap^em1cyagen
• Gene: Trpc4ap Location: Chr2:155476197-155534304 bp, - strand Genetic Position: Chr2, 77.26 cM, cytoband H2
• Alliance: Trpc4ap^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exons 2 and 4 produced a null allele. (J:300649)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trpc4ap Mutation: 36 strains or lines available

References

• Original: J:300649 Zhu Q, et al., TRUSS inhibition protects against high fat diet (HFD)-stimulated brain injury by alleviation of inflammatory response. Biochem Biophys Res Commun. 2019 Mar 26;511(1):41-48
• All: 1 reference(s)