Hmcn1^tm1.1Hamm
Targeted Allele Detail

Summary

• Symbol: Hmcn1^tm1.1Hamm
• Name: hemicentin 1; targeted mutation 1.1, Matthias Hammerschmidt
• MGI ID: MGI:6765431
• Gene: Hmcn1 Location: Chr1:150438275-150869186 bp, - strand Genetic Position: Chr1, 63.84 cM
• Alliance: Hmcn1^tm1.1Hamm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:310857
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 1 was replaced with an FRT flanked neo cassette via homologous recombination. Flp mediated recombination removed the neo cassette. (J:310857)

Expression

In Mice Carrying this Mutation:

10 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hmcn1 Mutation: 344 strains or lines available

References

• Original: J:310857 Welcker D, et al., Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions. Sci Rep. 2021 Sep 9;11(1):17926
• All: 1 reference(s)