Spaca4^tm1Osb
Targeted Allele Detail

Summary

• Symbol: Spaca4^tm1Osb
• Name: sperm acrosome associated 4; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6766531
• Gene: Spaca4 Location: Chr7:45374531-45375237 bp, - strand Genetic Position: Chr7, 29.46 cM
• Alliance: Spaca4^tm1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:311165
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance gene replaced the coding exon. (J:311165)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Spaca4 Mutation: 8 strains or lines available

References

• Original: J:311165 Fujihara Y, et al., The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2108777118
• All: 1 reference(s)