Mlxip^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mlxip^em1Smoc
• Name: MLX interacting protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6771649
• Synonyms: Mlxip^{em1(flox)Smoc}
• Gene: Mlxip Location: Chr5:123532861-123595995 bp, + strand Genetic Position: Chr5, 62.95 cM
• Alliance: Mlxip^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 2 and 3. (J:311109)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mlxip Mutation: 24 strains or lines available

References

• Original: J:311109 Lu Y, et al., MondoA-Thioredoxin-Interacting Protein Axis Maintains Regulatory T-Cell Identity and Function in Colorectal Cancer Microenvironment. Gastroenterology. 2021 Aug;161(2):575-591.e16
• All: 1 reference(s)