Rr88^em1Jkim
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr88^em1Jkim
• Name: regulatory region 88; endonuclease-mediated mutation 1, Joomyeong Kim
• MGI ID: MGI:6780710
• Synonyms: Peg3^U1, U1deltaR
• Gene: Rr88 Location: unknown Genetic Position: Chr7, Syntenic
• Alliance: Rr88^em1Jkim page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-mediated mutation deleted 997 bp within the Oocyte-specific U1 promoter 20 kb upstream of the Peg3 DMR (differentially methylated region). (J:265949)

Expression

In Mice Carrying this Mutation:

20 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr88 Mutation: 0 strains or lines available

References

• Original: J:265949 Bretz CL, et al., Transcription-driven DNA methylation setting on the mouse Peg3 locus. Epigenetics. 2017;12(11):945-952
• All: 4 reference(s)