Tgfbrap1^tm1Gsk
Targeted Allele Detail

Summary

• Symbol: Tgfbrap1^tm1Gsk
• Name: transforming growth factor, beta receptor associated protein 1; targeted mutation 1, GlaxoSmithKline
• MGI ID: MGI:6783436
• Gene: Tgfbrap1 Location: Chr1:43086360-43137788 bp, - strand Genetic Position: Chr1, 22.13 cM
• Alliance: Tgfbrap1^tm1Gsk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:312182
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced 594 bp of exon 1 with a neomycin resistance cassette. (J:312182)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tgfbrap1 Mutation: 39 strains or lines available

References

• Original: J:312182 Messler S, et al., The TGF-beta signaling modulators TRAP1/TGFBRAP1 and VPS39/Vam6/TLP are essential for early embryonic development. Immunobiology. 2011;261(3):343-50
• All: 2 reference(s)