Vps39^tm1Gsk
Targeted Allele Detail

Summary

• Symbol: Vps39^tm1Gsk
• Name: VPS39 HOPS complex subunit; targeted mutation 1, GlaxoSmithKline
• MGI ID: MGI:6783440
• Gene: Vps39 Location: Chr2:120146942-120183618 bp, - strand Genetic Position: Chr2, 60.31 cM
• Alliance: Vps39^tm1Gsk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:312182
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced part of exon 2 with an EGFP reporter gene and floxed neomycin resistance cassette. (J:312182)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vps39 Mutation: 50 strains or lines available

References

• Original: J:312182 Messler S, et al., The TGF-beta signaling modulators TRAP1/TGFBRAP1 and VPS39/Vam6/TLP are essential for early embryonic development. Immunobiology. 2011;261(3):343-50
• All: 2 reference(s)