Cfap161^tm1.2Gos
Targeted Allele Detail

Summary

• Symbol: Cfap161^tm1.2Gos
• Name: cilia and flagella associated protein 161; targeted mutation 1.2, Achim Gossler
• MGI ID: MGI:6783445
• Synonyms: Cfap161^deltaex2,3, Cfap161^tm1.2Cgen, Cfap161^tm1.2Cya
• Gene: Cfap161 Location: Chr7:83423309-83444088 bp, - strand Genetic Position: Chr7, 47.74 cM
• Alliance: Cfap161^tm1.2Gos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307371
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exons 2 and 3. Western blot analysis confirmed the absence of protein expression in testis and epididymis lysates from homozygous mice. (J:307371)

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cfap161 Mutation: 24 strains or lines available

References

• Original: J:307371 Beckers A, et al., The highly conserved FOXJ1 target CFAP161 is dispensable for motile ciliary function in mouse and Xenopus. Sci Rep. 2021 Jun 25;11(1):13333
• All: 1 reference(s)