Tg(Zbtb7b/CD4-cre,-CD2)#Tani
Transgene Detail

Summary

• Symbol: Tg(Zbtb7b/CD4-cre,-CD2)#Tani
• Name: transgene insertion, Ichiro Taniuchi
• MGI ID: MGI:6784021
• Synonyms: ThPOK-Cre
• Transgene: Tg(Zbtb7b/CD4-cre,-CD2)#Tani Location: unknown
• Alliance: Tg(Zbtb7b/CD4-cre,-CD2)#Tani page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Epitope tag, Recombinase)
• Mutation: Insertion
• Tg(Zbtb7b/CD4-cre,-CD2)#Tani expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Zbtb7b (MGI:102755)

• Mutation details: A 562base pair fragment of the Zbtb7b silencer sequence was inserted into a mini-transgene containing the minimal Cd4 enhancer-promoter-cre. The sequence encoding an internal ribosomal entry site and human CD2 were also inserted downstream of the cDNA cassette encoding Cre. The transgene expresses Cre specifically in the CD4 lineage. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:193392)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Zbtb7b (mouse) Summary of all recombinase alleles driven by Zbtb7b. Alliance mouse Zbtb7b gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:193392 Mucida D, et al., Transcriptional reprogramming of mature CD4(+) helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes. Nat Immunol. 2013 Mar;14(3):281-9
• All: 3 reference(s)