Tg(Prnp-UBQLN2)WT-lowHlp
Transgene Detail
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| Symbol: |
Tg(Prnp-UBQLN2)WT-lowHlp |
| Name: |
transgene insertion WT-low, Henry L Paulson |
| MGI ID: |
MGI:6784047 |
| Transgene: |
Tg(Prnp-UBQLN2)WT-lowHlp Location: unknown
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| Alliance: |
Tg(Prnp-UBQLN2)WT-lowHlp page
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| Strain of Origin: |
(C57BL/6 x SJL)F2
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| Transgene Type: |
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Transgenic (Epitope tag, Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The transgene contains the following elements: the mouse prion protein gene promoter and exon 1, intron 1 and exon 2, sequence coding for a FLAG tag in-frame with the human UBQLN2 cDNA, and Prnp exon 3 and downstream sequence. This allele expresses low levels of transgenic peptide.
(J:267076)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:267076 Sharkey LM, et al., Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10495-E10504 |
| All: |
4 reference(s) |
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Analysis Tools
