Tg(Cdh6-cre/ERT2)8Inot
Transgene Detail

Summary

• Symbol: Tg(Cdh6-cre/ERT2)8Inot
• Name: transgene insertion 8, Takayoshi Inoue
• MGI ID: MGI:6784069
• Synonyms: Cdh6-BAC-CreERT2
• Transgene: Tg(Cdh6-cre/ERT2)8Inot Location: unknown
• Alliance: Tg(Cdh6-cre/ERT2)8Inot page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Cdh6-cre/ERT2)8Inot expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cdh6 (MGI:107435)

• Mutation details: A LacZ reporter gene with the nuclear localization signal (NLS) followed by a polyadenylation sequence, was inserted into BAC clone RP23-78N21 with the 3' coverage of the Cdh6 locus that contains cis-regulatory modules for the somatosensory at the initiating ATG codon of the first coding exon of the Cdh6 gene. Eight founders were generated with similar expression patterns. Line 8 showing the highest level of CreERT2 protein expression in brain lysate was chosen for the studies. (J:205104)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cdh6 (mouse) Summary of all recombinase alleles driven by Cdh6. Alliance mouse Cdh6 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:205104 Terakawa YW, et al., A sharp cadherin-6 gene expression boundary in the developing mouse cortical plate demarcates the future functional areal border. Cereb Cortex. 2013 Oct;23(10):2293-308
• All: 1 reference(s)