Slc25a24^tm1Sinos
Targeted Allele Detail

Summary

• Symbol: Slc25a24^tm1Sinos
• Name: solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24; targeted mutation 1, Satoshi Inoue
• MGI ID: MGI:6790249
• Gene: Slc25a24 Location: Chr3:109030465-109075725 bp, + strand Genetic Position: Chr3, 48.13 cM
• Alliance: Slc25a24^tm1Sinos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:312208
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced exon 2 with a neomycin resistance cassette. Bruce-4; Chimeras were mated to C57BL/6J (J:312208)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc25a24 Mutation: 22 strains or lines available

References

• Original: J:312208 Urano T, et al., SLC25A24 as a novel susceptibility gene for low fat mass in humans and mice. J Clin Endocrinol Metab. 2015 Apr;100(4):E655-63
• All: 1 reference(s)