Irgm1^em1Myam
Endonuclease-mediated Allele Detail

Summary

• Symbol: Irgm1^em1Myam
• Name: immunity-related GTPase family M member 1; endonuclease-mediated mutation 1, Masahiro Yamamoto
• MGI ID: MGI:6790261
• Gene: Irgm1 Location: Chr11:48756072-48762247 bp, - strand Genetic Position: Chr11, 28.84 cM, cytoband B1.2
• Alliance: Irgm1^em1Myam page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of the second coding exon deleted 4 bp to generate a null allele (J:312451)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Irgm1 Mutation: 26 strains or lines available

Notes

This allele was targeted at the same time as Igtp^em1Myam.

References

• Original: J:312451 Lee Y, et al., p62 Plays a Specific Role in Interferon-gamma-Induced Presentation of a Toxoplasma Vacuolar Antigen. Toxoplasma Vacuolar Antigen. 2015;13(3):223-33
• All: 3 reference(s)