Tg(Epx-EYFP/cre)#Voeh
Transgene Detail

Summary

• Symbol: Tg(Epx-EYFP/cre)#Voeh
• Name: transgene insertion, David Voehringer
• MGI ID: MGI:6790413
• Synonyms: EpxCre
• Transgene: Tg(Epx-EYFP/cre)#Voeh Location: unknown
• Alliance: Tg(Epx-EYFP/cre)#Voeh page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Epx-EYFP/cre)#Voeh expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Epx (MGI:107569)

• Mutation details: A transgene consists of a BAC clone 193P5 (encoding the eosinophil peroxidase gene Epx) of the mouse genomic BAC library RPCI-23 modified to insert an eYFP-Cre fusion protein cassette directly after the start codon of Epx by homologous recombination in bacteria. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. While cre activity was preserved in the transgenic mice, the eYFP fluorescence was lost. (J:224642)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Epx (mouse) Summary of all recombinase alleles driven by Epx. Comparative matrix view of recombinase activities Alliance mouse Epx gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:224642 Schwartz C, et al., Eosinophil-specific deletion of IkappaBalpha in mice reveals a critical role of NF-kappaB-induced Bcl-xL for inhibition of apoptosis. Blood. 2015 Jun 18;125(25):3896-904
• All: 1 reference(s)