Pmel^{tm1(cre/ERT2)Jkn}
Targeted Allele Detail

Summary

• Symbol: Pmel^{tm1(cre/ERT2)Jkn}
• Name: premelanosome protein; targeted mutation 1, Ian J Jackson
• MGI ID: MGI:6791291
• Synonyms: Pmel::CreERT2, Pmel^CreERT2
• Gene: Pmel Location: Chr10:128540064-128556107 bp, + strand Genetic Position: Chr10, 77.13 cM
• Alliance: Pmel^{tm1(cre/ERT2)Jkn} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:235817
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Pmel^{tm1(cre/ERT2)Jkn} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pmel (MGI:98301)

• The allele is a cre/ERT2 knock-in at the Pmel gene. No detail was given. (J:235817)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pmel (mouse) Summary of all recombinase alleles driven by Pmel. Alliance mouse Pmel gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pmel Mutation: 38 strains or lines available

References

• Original: J:235817 Mort RL, et al., Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model. Nat Commun. 2016 Jan 06;7:10288
• All: 1 reference(s)