Ppm1h^tm1Tac
Targeted Allele Detail

Summary

• Symbol: Ppm1h^tm1Tac
• Name: protein phosphatase 1H (PP2C domain containing); targeted mutation 1, Taconic
• MGI ID: MGI:6794071
• Gene: Ppm1h Location: Chr10:122514667-122781700 bp, + strand Genetic Position: Chr10, 70.44 cM
• Alliance: Ppm1h^tm1Tac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:312767
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• The selection cassette inserted at the translation initiation site. (J:312767)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppm1h Mutation: 32 strains or lines available

References

• Original: J:312767 Khan SS, et al., Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain. Elife. 2021 Oct 18;10:e67900
• All: 1 reference(s)