Gm40600^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gm40600^em1Cya
• Name: predicted gene, 40600; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6794076
• Synonyms: Gm40600^em1Cgen, Gm40600 KO
• Gene: Gm40600 Location: unknown Genetic Position: Chr10, Syntenic
• Alliance: Gm40600^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Mutation details: The gene was targeted with two pairs of sgRNAs, up- and downstream of the locus, using CRISPR/Cas9 technology, resulting in the deletion of the locus through various sized deletion-insertions (7638 bp del with 13 bp ins or 7653 bp del with 1 bp ins). (J:311878)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gm40600 Mutation: 0 strains or lines available

References

• Original: J:311878 He Y, et al., Gm40600 promotes CD4(+) T-cell responses by interacting with Ahnak. Immunology. 2021 Sep;164(1):190-206
• All: 1 reference(s)