Gnat2^cpfl3-2J
Spontaneous Allele Detail

Summary

• Symbol: Gnat2^cpfl3-2J
• Name: G protein subunit alpha transducin 2; cone photoreceptor function loss 3, 2 Jackson
• MGI ID: MGI:6798111
• Synonyms: Gnat2^cpfl10
• Gene: Gnat2 Location: Chr3:108000105-108008748 bp, + strand Genetic Position: Chr3, 46.83 cM
• Alliance: Gnat2^cpfl3-2J page

Mutation origin

• Strain of Origin: B10.129S2(B6)-Il3^tm1Tyb/J

Mutation description

• Allele Type: Spontaneous (Not Specified)
• Mutation: Single point mutation
• Mutation details: a spontaneous single base pair change C to T in exon 2 results in a change at codon 24 from CAG to a TAG stop codon.
• Inheritance: Recessive

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gnat2 Mutation: 35 strains or lines available

References

• Original: J:313437 Chang B, et al., A new mouse model of cone photoreceptor function loss (cpfl10) with normal rod photoreceptor function. Invest Ophthalmol Vis Sci. 2020 Jun;61(7):768 (Abstr.)
• All: 1 reference(s)