Necab1^tm1(cre)Ahan
Targeted Allele Detail

Summary

• Symbol: Necab1^tm1(cre)Ahan
• Name: N-terminal EF-hand calcium binding protein 1; targeted mutation 1, Adam W Hantman
• MGI ID: MGI:6810745
• Synonyms: Necab1-Cre
• Gene: Necab1 Location: Chr4:14952245-15149794 bp, - strand Genetic Position: Chr4, 6.45 cM
• Alliance: Necab1^tm1(cre)Ahan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:312548
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Necab1^tm1(cre)Ahan expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Necab1 (MGI:1916602)

• Mutation details: Using homologous recombination in ES cells derived from a 129S6 x C57BL/6J F1 hybrid embryos, cre placed under the control of Necab1 promoter. (J:312548)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Necab1 (mouse) Summary of all recombinase alleles driven by Necab1. Comparative matrix view of recombinase activities Alliance mouse Necab1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Necab1 Mutation: 23 strains or lines available

References

• Original: J:312548 Hay YA, et al., Thalamus mediates neocortical Down state transition via GABAB-receptor-targeting interneurons. Neuron. 2021 Sep 1;109(17):2682-2690.e5
• All: 2 reference(s)