Setd4^em1(cre)Wjy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Setd4^em1(cre)Wjy
• Name: SET domain containing 4; endonuclease-mediated mutation 1, Wei-Jun Yang
• MGI ID: MGI:6822324
• Synonyms: SETD4-Cre
• Gene: Setd4 Location: Chr16:93380345-93400951 bp, - strand Genetic Position: Chr16, 54.52 cM
• Alliance: Setd4^em1(cre)Wjy page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Setd4^em1(cre)Wjy expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Setd4 (MGI:2136890)

• Mutation details: Using CRISPR/Cas9 technology, a T2A-Cre-WPRE-PA cassette was inserted into the 3'-end SETD4 coding region. (J:314227)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Setd4 (mouse) Summary of all recombinase alleles driven by Setd4. Comparative matrix view of recombinase activities Alliance mouse Setd4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Setd4 Mutation: 30 strains or lines available

References

• Original: J:314227 Tian JZ, et al., SETD4-expressing cells contribute to pancreatic development and response to cerulein induced pancreatitis injury. Sci Rep. 2021 Jun 15;11(1):12614
• All: 4 reference(s)