Rab29^{tm1b(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Rab29^{tm1b(EUCOMM)Wtsi}
• Name: RAB29, member RAS oncogene family; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:6825753
• Gene: Rab29 Location: Chr1:131794962-131800625 bp, + strand Genetic Position: Chr1, 57.21 cM
• Alliance: Rab29^{tm1b(EUCOMM)Wtsi} page
• IMPC: Rab29 gene page

Mutation origin

• Mutant Cell Line: EPD0418_1_B05
• Germline Transmission: Earliest citation of germline transmission: J:314451
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The construct is generated from a L1L2_Bact_P cassette inserted at position 131797953 of Chromosome 1 upstream of exon 4. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 4. Cre-mediated recombination removed the neo cassette and exon 4..

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rab29 Mutation: 22 strains or lines available

References

• Original: J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010
• All: 3 reference(s)