Cmip^tm1.1Ics
Targeted Allele Detail

Summary

• Symbol: Cmip^tm1.1Ics
• Name: c-Maf inducing protein; targeted mutation 1.1, Mouse Clinical Institute
• MGI ID: MGI:6827378
• Synonyms: Cmip^lox
• Gene: Cmip Location: Chr8:117983803-118186169 bp, + strand Genetic Position: Chr8, 63.87 cM, cytoband E1
• Alliance: Cmip^tm1.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:313623
• Parent Cell Line: BD10 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a loxP site upstream of exon 6, and an FRT-flanked neomycin resistance cassette with a 3' loxP site. Flp-mediated removed the selection cassette and left exon 6 floxed. (J:313623)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cmip Mutation: 49 strains or lines available

References

• Original: J:313623 Moktefi A, et al., Repression of CMIP transcription by WT1 is relevant to podocyte health. Kidney Int. 2016 Dec;90(6):1298-1311
• All: 1 reference(s)