Glipr2^em1Blev
Endonuclease-mediated Allele Detail

Summary

• Symbol: Glipr2^em1Blev
• Name: GLI pathogenesis-related 2; endonuclease-mediated mutation 1, Beth Levine
• MGI ID: MGI:6828739
• Gene: Glipr2 Location: Chr4:43957702-43979118 bp, + strand Genetic Position: Chr4, 23.07 cM, cytoband B1
• Alliance: Glipr2^em1Blev page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISRP-targeting of exon 2 deleted 8 bp starting at nucleotide 40. (J:312370)

Expression

In Mice Carrying this Mutation:

13 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Glipr2 Mutation: 37 strains or lines available

References

• Original: J:312370 Zhao Y, et al., GLIPR2 is a negative regulator of autophagy and the BECN1-ATG14-containing phosphatidylinositol 3-kinase complex. Autophagy. 2021 Oct;17(10):2891-2904
• All: 1 reference(s)