Mirc13^tm1Biat
Targeted Allele Detail

Summary

• Symbol: Mirc13^tm1Biat
• Name: microRNA cluster 13, including Mir141 through Mir200c; targeted mutation 1, Biomodels Austria
• MGI ID: MGI:6828804
• Synonyms: 141/200c^-
• Gene: Mirc13 Location: Chr6:124694877-124695353 bp Genetic Position: Chr6, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314874
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mirc13^tm1Biat involves 2 genes/genome features (Mir141, Mir200c) View all
• The targeting construct replaced the microRNA sequences with a neomycin resistance cassette. (J:314874)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc13 Mutation: 3 strains or lines available

References

• Original: J:314874 Belgardt BF, et al., The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes. Nat Med. 2015;21(6):619-27
• All: 2 reference(s)