Tg(Ins2-Mirc13)E4Biat
Transgene Detail

Summary

• Symbol: Tg(Ins2-Mirc13)E4Biat
• Name: transgene insertion E4, Biomodels Austria
• MGI ID: MGI:6828985
• Synonyms: Rip141/200c
• Transgene: Tg(Ins2-Mirc13)E4Biat Location: unknown
• Alliance: Tg(Ins2-Mirc13)E4Biat page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ins2-Mirc13)E4Biat expresses 2 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mir141 (MGI:2676826)
  mouse	Mir200c (MGI:3618750)

• Tg(Ins2-Mirc13)E4Biat expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Ins2 (24506)

  Ins2	(MGI:96573)

• Mutation details: The transgene contains the rat promoter driving expression of a 819bp fragment containing the mouse sequence. Three founders were generated (E4, E44, and E46). Line E4 is the representative line. (J:314874)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:314874 Belgardt BF, et al., The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes. Nat Med. 2015;21(6):619-27
• All: 2 reference(s)