Surf4^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Surf4^em1Bcgen
• Name: surfeit gene 4; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:6830906
• Synonyms: Surf4^fl
• Gene: Surf4 Location: Chr2:26810052-26823801 bp, - strand Genetic Position: Chr2, 19.1 cM
• Alliance: Surf4^em1Bcgen page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 2. (J:302969)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Surf4 Mutation: 18 strains or lines available

References

• Original: J:302969 Wang X, et al., Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans. Cell Metab. 2021 Feb 2;33(2):350-366.e7
• All: 6 reference(s)