Mcrip2^em1Eno
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mcrip2^em1Eno
• Name: MAPK regulated corepressor interacting protein 2; endonuclease-mediated mutation 1, Eric N Olson
• MGI ID: MGI:6845074
• Gene: Mcrip2 Location: Chr17:26082672-26087738 bp, - strand Genetic Position: Chr17, 12.96 cM, cytoband B1
• Alliance: Mcrip2^em1Eno page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of exon 3 deleted 93 bp (29 bp from the 3' end of intron 2 and 64 bp from the 5' end of exon 3), introducing a premature stop codon. (J:316902)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mcrip2 Mutation: 5 strains or lines available

References

• Original: J:316902 Cannavino J, et al., Regulation of cold-induced thermogenesis by the RNA binding protein FAM195A. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2104650118
• All: 1 reference(s)