Spata33^em2Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spata33^em2Osb
• Name: spermatogenesis associated 33; endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6849783
• Synonyms: Spata33^-9087
• Gene: Spata33 Location: Chr8:123939572-123948784 bp, + strand Genetic Position: Chr8, 72.08 cM
• Alliance: Spata33^em2Osb page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exons 1 and 3 deleted 9087 bp. (J:309565)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Spata33 Mutation: 17 strains or lines available

References

• Original: J:309565 Miyata H, et al., SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice. Proc Natl Acad Sci U S A. 2021 Aug 31;118(35):e2106673118
• All: 1 reference(s)