Cklf^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cklf^em1Osb
• Name: chemokine-like factor; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6849787
• Synonyms: Cklf^-6257+1
• Gene: Cklf Location: Chr8:104977493-104991570 bp, + strand Genetic Position: Chr8, 53.04 cM
• Alliance: Cklf^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• CRISPR-targeting of exon 2 and intron 4 deleted 6257 bp and inserted 1 bp. (J:309565)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cklf Mutation: 21 strains or lines available

References

• Original: J:309565 Miyata H, et al., SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice. Proc Natl Acad Sci U S A. 2021 Aug 31;118(35):e2106673118
• All: 1 reference(s)