Dbh^tm1(cre)Sath
Targeted Allele Detail

Summary

• Symbol: Dbh^tm1(cre)Sath
• Name: dopamine beta hydroxylase; targeted mutation 1, Steven A Thomas
• MGI ID: MGI:6850023
• Synonyms: Dbh^Cre, Dbh^IRES-Cre
• Gene: Dbh Location: Chr2:27055519-27073216 bp, + strand Genetic Position: Chr2, 19.29 cM
• Alliance: Dbh^tm1(cre)Sath page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239889
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Dbh^tm1(cre)Sath expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Dbh (MGI:94864)

• Mutation details: IRES-Cre was targeted to a site just downstream of the termination codon in the last exon of Dbh locus. (J:239889)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dbh (mouse) Summary of all recombinase alleles driven by Dbh. Comparative matrix view of recombinase activities Alliance mouse Dbh gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dbh Mutation: 17 strains or lines available

References

• Original: J:239889 Roman CW, et al., Genetically and functionally defined NTS to PBN brain circuits mediating anorexia. Nat Commun. 2016 Jun 15;7:11905
• All: 2 reference(s)