Tspyl2^tm1.2Yph
Targeted Allele Detail

Summary

• Symbol: Tspyl2^tm1.2Yph
• Name: TSPY-like 2; targeted mutation 1.2, Yi-Ping Hsueh
• MGI ID: MGI:6852745
• Gene: Tspyl2 Location: ChrX:151119848-151125421 bp, - strand Genetic Position: ChrX, 68.46 cM, cytoband F2
• Alliance: Tspyl2^tm1.2Yph page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:302078
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct inserted upstream of exon 1 a lox P site and downstream of exon 1 an FRT-flanked neomycin resistance cassette with a 3 prime loxP site. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 1. (J:302078)

Expression

In Mice Carrying this Mutation:

162 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tspyl2 Mutation: 6 strains or lines available

References

• Original: J:302078 Chung WC, et al., Targeted deletion of CASK-interacting nucleosome assembly protein causes higher locomotor and exploratory activities. Neurosignals. 2011;19(3):128-41
• All: 1 reference(s)