Lyplal1^em1Espel
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lyplal1^em1Espel
• Name: lysophospholipase-like 1; endonuclease-mediated mutation 1, Elizabeth Speliotes
• MGI ID: MGI:6856579
• Gene: Lyplal1 Location: Chr1:185819929-185849507 bp, - strand Genetic Position: Chr1, 89.81 cM
• Alliance: Lyplal1^em1Espel page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted a single base from exon 1. (J:340413)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lyplal1 Mutation: 25 strains or lines available

References

• Original: J:340413 Vohnoutka RB, et al., Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity. J Mol Endocrinol. 2023 Apr 1;70(3):e220131
• All: 1 reference(s)