C1ql2^em1(cre)Gfng
Endonuclease-mediated Allele Detail

Summary

• Symbol: C1ql2^em1(cre)Gfng
• Name: complement component 1, q subcomponent-like 2; endonuclease-mediated mutation 1, Guoping Feng
• MGI ID: MGI:6856619
• Synonyms: C1QL2-IRES-Cre
• Gene: C1ql2 Location: Chr1:120268312-120270903 bp, + strand Genetic Position: Chr1, 52.68 cM
• Alliance: C1ql2^em1(cre)Gfng page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• C1ql2^em1(cre)Gfng expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	C1ql2 (MGI:3032521)

• Mutation details: An IRES-Cre-pA cassette was introduced immediately after the stop codon of the mouse C1ql2 gene in C57BL/6NTac embryos using CRISPR/Cas9 methodologies. (J:317610)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	C1ql2 (mouse) Summary of all recombinase alleles driven by C1ql2. Comparative matrix view of recombinase activities Alliance mouse C1ql2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any C1ql2 Mutation: 12 strains or lines available

References

• Original: J:317610 Roy DS, et al., Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models. Neuron. 2021 Aug 18;109(16):2590-2603.e13
• All: 2 reference(s)