Tg(Myh11-dre/ERT2)#Cya
Transgene Detail

Summary

• Symbol: Tg(Myh11-dre/ERT2)#Cya
• Name: transgene insertion, Cyagen Biosciences
• MGI ID: MGI:6860615
• Synonyms: Myh11-DreERT2, Tg(Myh11-dre/ERT2)#Cgen
• Transgene: Tg(Myh11-dre/ERT2)#Cya Location: unknown
• Alliance: Tg(Myh11-dre/ERT2)#Cya page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Myh11-dre/ERT2)#Cya expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Myh11 (MGI:102643)

• Mutation details: The myosin heavy chain 11 (Myh11) promoter was placed upstream of a Dre recombinase fused to an ERT2 (estrogen receptor 2) domain. (J:318676)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Myh11 (mouse) Summary of all recombinase alleles driven by Myh11. Comparative matrix view of recombinase activities Alliance mouse Myh11 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:318676 Alencar GF, et al., Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis. Circulation. 2020 Nov 24;142(21):2045-2059
• All: 2 reference(s)