Fam120b^em1Qqlg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fam120b^em1Qqlg
• Name: family with sequence similarity 120, member B; endonuclease-mediated mutation 1, Qinqiang Long
• MGI ID: MGI:6863921
• Gene: Fam120b Location: Chr17:15616464-15653843 bp, + strand Genetic Position: Chr17, 8.95 cM
• Alliance: Fam120b^em1Qqlg page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting of exon 2 produced a null allele. (J:318650)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fam120b Mutation: 37 strains or lines available

References

• Original: J:318650 Liu Z, et al., San1 deficiency leads to cardiomyopathy due to excessive R-loop-associated DNA damage and cardiomyocyte hypoplasia. Biochim Biophys Acta Mol Basis Dis. 2021 Nov 1;1867(11):166237
• All: 1 reference(s)