Lbx1^em1Mwil
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lbx1^em1Mwil
• Name: ladybird homeobox 1; endonuclease-mediated mutation 1, Megan J Wilson
• MGI ID: MGI:6864154
• Synonyms: Lbx1^delta
• Gene: Lbx1 Location: Chr19:45221123-45224251 bp, - strand Genetic Position: Chr19, 38.61 cM, cytoband D
• Alliance: Lbx1^em1Mwil page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Using the CRISPR-Cas9 gene-editing system, a deletion of 7 bp in the coding sequence of the Lbx1 gene creates an early stop codon. (J:319391)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lbx1 Mutation: 13 strains or lines available

References

• Original: J:319391 Decourtye L, et al., Characterization of a novel Lbx1 mouse loss of function strain. Differentiation. 2021 Dec 9;123:30-41
• All: 1 reference(s)