Fam209^em2Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fam209^em2Osb
• Name: family with sequence similarity 209; endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6866939
• Synonyms: Fam209⁺¹
• Gene: Fam209 Location: Chr2:172314474-172316236 bp, + strand Genetic Position: Chr2, 94.87 cM, cytoband H3
• Alliance: Fam209^em2Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting of exon 1 inserted 1 bp, resulting in a frameshift mutation. (J:319865)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Fam209 Mutation: 24 strains or lines available

References

• Original: J:319865 Castaneda JM, et al., FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice. J Cell Sci. 2021 Nov 1;134(21):jcs259206
• All: 1 reference(s)