Zfta^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Zfta^{tm1.1(KOMP)Vlcg}
• Name: zinc finger translocation associated; targeted mutation 1.1, Velocigene
• MGI ID: MGI:6867026
• Gene: Zfta Location: Chr19:7394990-7403269 bp, + strand Genetic Position: Chr19, 5.32 cM
• Alliance: Zfta^{tm1.1(KOMP)Vlcg} page
• IMPC: Zfta gene page

Mutation origin

• Mutant Cell Line: 12886A-A12
• Germline Transmission: Earliest citation of germline transmission: J:319546
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1699bp between positions 7398808-7400506 of Chromosome 19 (Build GRCm39). Cre-mediated recombination removed the selection cassette. (J:319546)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfta Mutation: 18 strains or lines available

References

• Original: J:319546 Herranz-Perez V, et al., Ependymoma associated protein Zfta is expressed in immature ependymal cells but is not essential for ependymal development in mice. Sci Rep. 2022 Jan 27;12(1):1493
• All: 1 reference(s)