Pwwp2b^tm1.1Bcgen
Targeted Allele Detail

Summary

• Symbol: Pwwp2b^tm1.1Bcgen
• Name: PWWP domain containing 2B; targeted mutation 1.1, Biocytogen LLC
• MGI ID: MGI:6867219
• Synonyms: Pwwp2b^flox
• Gene: Pwwp2b Location: Chr7:138828398-138847172 bp, + strand Genetic Position: Chr7, 84.39 cM
• Alliance: Pwwp2b^tm1.1Bcgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:319940
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exon 2. Recombination removed the selection cassette. (J:319940)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pwwp2b Mutation: 34 strains or lines available

References

• Original: J:319940 Yan L, et al., PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex. Adv Sci (Weinh). 2021 Aug;8(16):e2102060
• All: 1 reference(s)