Igdcc4^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Igdcc4^em1Bcgen
• Name: immunoglobulin superfamily, DCC subclass, member 4; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:6867809
• Gene: Igdcc4 Location: Chr9:65008768-65045222 bp, + strand Genetic Position: Chr9, 35.1 cM
• Alliance: Igdcc4^em1Bcgen page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-mediated recombination created an approximately 26 kb deletion spanning from exon 2 to exon 20. (J:320015)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igdcc4 Mutation: 69 strains or lines available

References

• Original: J:320015 Song Y, et al., A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis. PLoS Pathog. 2021 Dec;17(12):e1010141
• All: 1 reference(s)