Loxl4em1Bcgen
Endonuclease-mediated Allele Detail
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| Symbol: |
Loxl4em1Bcgen |
| Name: |
lysyl oxidase-like 4; endonuclease-mediated mutation 1, Biocytogen LLC |
| MGI ID: |
MGI:6867825 |
| Synonyms: |
Loxl4-, Loxl4-KO |
| Gene: |
Loxl4 Location: Chr19:42582421-42601252 bp, - strand Genetic Position: Chr19, 36.56 cM, cytoband D1
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| Alliance: |
Loxl4em1Bcgen page
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Endonuclease-mediated (Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: CRISPR-mediated recombination created a deletion that spanned exons 2 to 14, as confirmed by genomic PCR and Western blotting in aorta smooth muscle cells and heart endothelial cells.
(J:319500)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Loxl4 Mutation: |
38 strains or lines available
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| Original: |
J:319500 Li H, et al., LOXL4 Abrogation Does Not Exaggerate Angiotensin II-Induced Thoracic or Abdominal Aortic Aneurysm in Mice. Genes (Basel). 2021 Mar 31;12(4) |
| All: |
1 reference(s) |
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Analysis Tools
