Btnl2^em1Wche
Endonuclease-mediated Allele Detail

Summary

• Symbol: Btnl2^em1Wche
• Name: butyrophilin-like 2; endonuclease-mediated mutation 1, Chenhui Wang
• MGI ID: MGI:6885845
• Gene: Btnl2 Location: Chr17:34573796-34588469 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: Btnl2^em1Wche page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 1 to 3. (J:321348)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Btnl2 Mutation: 31 strains or lines available

References

• Original: J:321348 Du Y, et al., Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing gammadelta T cells. Nat Commun. 2022 Jan 11;13(1):231
• All: 1 reference(s)