Cckar^em1(cre)Shah
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cckar^em1(cre)Shah
• Name: cholecystokinin A receptor; endonuclease-mediated mutation 1, Nirao Shah
• MGI ID: MGI:6885886
• Synonyms: Cckar^Cre
• Gene: Cckar Location: Chr5:53855827-53865046 bp, - strand Genetic Position: Chr5, 29.52 cM
• Alliance: Cckar^em1(cre)Shah page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Cckar^em1(cre)Shah expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cckar (MGI:99478)

• Mutation details: Using CRISPR/Cas9-mediated homologous recombination, the 2A-cre was inserted into the 3'UTR in exon 5 of the Cckar gene. (J:321365)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cckar (mouse) Summary of all recombinase alleles driven by Cckar. Comparative matrix view of recombinase activities Alliance mouse Cckar gene page

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cckar Mutation: 41 strains or lines available

References

• Original: J:321365 Knoedler JR, et al., A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior. Cell. 2022 Feb 17;185(4):654-671.e22
• All: 2 reference(s)